Prevalence and Characteristics of Familial Hyperaldosteronism

Primary aldosteronism (PA) is the most frequent cause of secondary hypertension, and patients display an increased prevalence of cardiovascular events compared with essential hypertensives. To date, 3 familial forms of PA have been described and termed familial hyperaldosteronism types I, II, and III (FH-I to -III). The aim of this study was to investigate the prevalence and clinical characteri...

متن کامل

Prevalence and characteristics of familial hyperaldosteronism: the PATOGEN study (Primary Aldosteronism in TOrino-GENetic forms).

Primary aldosteronism (PA) is the most frequent cause of secondary hypertension, and patients display an increased prevalence of cardiovascular events compared with essential hypertensives. To date, 3 familial forms of PA have been described and termed familial hyperaldosteronism types I, II, and III (FH-I to -III). The aim of this study was to investigate the prevalence and clinical characteri...

متن کامل

Familial hyperaldosteronism.

Aldosterone, the major circulating mineralocorticoid, participates in blood volume and serum potassium homeostasis. Primary aldosteronism is a disorder characterised by hypertension and hypokalaemia due to autonomous aldosterone secretion from the adrenocortical zona glomerulosa. Improved screening techniques, particularly application of the plasma aldosterone:plasma renin activity ratio, have ...

متن کامل

An Update on Familial Hyperaldosteronism

▼ Familial forms of primary aldosteronism have been suggested to account for up to 6 % of cases in referral centers. For many years, the genetics of familial hyperaldosteronism remained unknown, with the notable exception of glucocorticoid-remediable aldosteronism, due to unequal crossing over and formation of a chimeric 11β-hydroxylase/ aldosterone synthase gene. Over the past 5 years, mutatio...

متن کامل

An Update on Familial Hyperaldosteronism

▼ Familial forms of primary aldosteronism have been suggested to account for up to 6 % of cases in referral centers. For many years, the genetics of familial hyperaldosteronism remained unknown, with the notable exception of glucocorticoid-remediable aldosteronism, due to unequal crossing over and formation of a chimeric 11β-hydroxylase/ aldosterone synthase gene. Over the past 5 years, mutatio...

متن کامل

Prevalence and Characteristics of Familial Hyperaldosteronism

نویسندگان

چکیده

برای دانلود باید عضویت طلایی داشته باشید

منابع مشابه